CovidSeniorV1, Main, Exploration, bibRecord, 000146

The first 100 cases of COVID-19 in a Hospital in Madrid with a 2-month follow-up.

Identifieur interne : 000146 ( Main/Exploration ); précédent : 000145; suivant : 000147

The first 100 cases of COVID-19 in a Hospital in Madrid with a 2-month follow-up.

Auteurs : P. Mu Oz ; A. Galar [Espagne] ; P. Catalán ; M. Valerio ; T. Aldamiz-Echevarría ; C. C Lliga ; E. Bouza

Source :

Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia [ 1988-9518 ] ; 2020.

RBID : pubmed:32729288

Descripteurs français

KwdFr :
- Adulte (MeSH), Adulte d'âge moyen (MeSH), Betacoronavirus (MeSH), Comorbidité (MeSH), Enfant (MeSH), Espagne (épidémiologie), Facteurs temps (MeSH), Femelle (MeSH), Fièvre (étiologie), Hospitalisation (statistiques et données numériques), Humains (MeSH), Indice de masse corporelle (MeSH), Infections à coronavirus (diagnostic), Infections à coronavirus (mortalité), Infections à coronavirus (traitement médicamenteux), Infections à coronavirus (épidémiologie), Jeune adulte (MeSH), Mâle (MeSH), Pandémies (MeSH), Pneumopathie virale (diagnostic), Pneumopathie virale (mortalité), Pneumopathie virale (traitement médicamenteux), Pneumopathie virale (épidémiologie), Répartition par âge (MeSH), Sujet âgé (MeSH), Sujet âgé de 80 ans ou plus (MeSH), Techniques de laboratoire clinique (MeSH), Études de suivi (MeSH), Évaluation des symptômes (MeSH).
MESH :
- diagnostic : Infections à coronavirus, Pneumopathie virale.
- mortalité : Infections à coronavirus, Pneumopathie virale.
- statistiques et données numériques : Hospitalisation.
- traitement médicamenteux : Infections à coronavirus, Pneumopathie virale.
- épidémiologie : Espagne, Infections à coronavirus, Pneumopathie virale.
- étiologie : Fièvre.
- Adulte, Adulte d'âge moyen, Betacoronavirus, Comorbidité, Enfant, Facteurs temps, Femelle, Humains, Indice de masse corporelle, Jeune adulte, Mâle, Pandémies, Répartition par âge, Sujet âgé, Sujet âgé de 80 ans ou plus, Techniques de laboratoire clinique, Études de suivi, Évaluation des symptômes.
Wicri :
- geographic : Espagne.

English descriptors

KwdEn :
- Adult (MeSH), Age Distribution (MeSH), Aged (MeSH), Aged, 80 and over (MeSH), Betacoronavirus (MeSH), Body Mass Index (MeSH), Child (MeSH), Clinical Laboratory Techniques (MeSH), Comorbidity (MeSH), Coronavirus Infections (diagnosis), Coronavirus Infections (drug therapy), Coronavirus Infections (epidemiology), Coronavirus Infections (mortality), Female (MeSH), Fever (etiology), Follow-Up Studies (MeSH), Hospitalization (statistics & numerical data), Humans (MeSH), Male (MeSH), Middle Aged (MeSH), Pandemics (MeSH), Pneumonia, Viral (diagnosis), Pneumonia, Viral (drug therapy), Pneumonia, Viral (epidemiology), Pneumonia, Viral (mortality), Spain (epidemiology), Symptom Assessment (MeSH), Time Factors (MeSH), Young Adult (MeSH).
MESH :
- geographic , epidemiology : Spain.
- diagnosis : Coronavirus Infections, Pneumonia, Viral.
- drug therapy : Coronavirus Infections, Pneumonia, Viral.
- epidemiology : Coronavirus Infections, Pneumonia, Viral.
- etiology : Fever.
- mortality : Coronavirus Infections, Pneumonia, Viral.
- statistics & numerical data : Hospitalization.
- Adult, Age Distribution, Aged, Aged, 80 and over, Betacoronavirus, Body Mass Index, Child, Clinical Laboratory Techniques, Comorbidity, Female, Follow-Up Studies, Humans, Male, Middle Aged, Pandemics, Symptom Assessment, Time Factors, Young Adult.

Abstract

OBJECTIVE

There are few descriptions of the clinical presentation and evolution of consecutive SARS-CoV-2 infections with a long-enough follow up.

METHODS

Description of the first consecutive 100 patients with microbiologically-proven COVID-19 in a large hospital in Madrid, Spain including a minimum of two-month follow up.

RESULTS

The median age of the patients (52% males) was 61.5 years (IQR=39.5-82.0) and the median BMI was 28.8 kg/m2 (IQR=24.7-33.7). Overall 72% of the patients had one or more co-morbid conditions with a median age-adjusted Charlson index of 2 (IQR=0-5.7). Five patients (5%) were immunosuppressed. The most common symptoms at the time of diagnosis were fever (80.0%), cough (53.0%) and dyspnea (23.0%). The median O2 saturation at the time of first examination was 94% (IQR=90-97). Chest X-ray on admission was compatible with pneumonia in 63% of the cases (bilateral in 42% and unilateral in 21%). Overall, 30% were managed at home and 70% were admitted to the hospital. Thirteen patients were admitted to the ICU with a median of 11 days of stay in the Unit (IQR=6.0-28.0). CALL score of our population ranged from 4 to 13. Overall, 60.0% of patients received antibiotic treatment and 66.0%, empirical antiviral treatment, mainly with lopinavir/ritonavir (65%) or hydroxychloroquine (42%). Mortality, with a minimum of 60 days of follow up, was 23%. The median age of the deceased patients was 85 years (IQR=79-93).

CONCLUSIONS

We found a high mortality in the first 100 patients diagnosed with COVID-19 at our institution, associated with advanced age and the presence of serious underlying diseases.

DOI: 10.37201/req/072.2020
PubMed: 32729288
PubMed Central: PMC7528411

Affiliations:

Links toward previous steps (curation, corpus...)

to stream Main, to step Corpus: 000927
to stream Main, to step Curation: 000927

Le document en format XML

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<term>Infections à coronavirus (traitement médicamenteux)</term>
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<term>Pneumopathie virale (mortalité)</term>
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<term>Pneumopathie virale</term>
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<front><div type="abstract" xml:lang="en"><p><b>OBJECTIVE</b>
</p>
<p>There are few descriptions of the clinical presentation and evolution of consecutive SARS-CoV-2 infections with a long-enough follow up.</p>
</div>
<div type="abstract" xml:lang="en"><p><b>METHODS</b>
</p>
<p>Description of the first consecutive 100 patients with microbiologically-proven COVID-19 in a large hospital in Madrid, Spain including a minimum of two-month follow up.</p>
</div>
<div type="abstract" xml:lang="en"><p><b>RESULTS</b>
</p>
<p>The median age of the patients (52% males) was 61.5 years (IQR=39.5-82.0) and the median BMI was 28.8 kg/m2 (IQR=24.7-33.7). Overall 72% of the patients had one or more co-morbid conditions with a median age-adjusted Charlson index of 2 (IQR=0-5.7). Five patients (5%) were immunosuppressed. The most common symptoms at the time of diagnosis were fever (80.0%), cough (53.0%) and dyspnea (23.0%). The median O2 saturation at the time of first examination was 94% (IQR=90-97). Chest X-ray on admission was compatible with pneumonia in 63% of the cases (bilateral in 42% and unilateral in 21%). Overall, 30% were managed at home and 70% were admitted to the hospital. Thirteen patients were admitted to the ICU with a median of 11 days of stay in the Unit (IQR=6.0-28.0). CALL score of our population ranged from 4 to 13. Overall, 60.0% of patients received antibiotic treatment and 66.0%, empirical antiviral treatment, mainly with lopinavir/ritonavir (65%) or hydroxychloroquine (42%). Mortality, with a minimum of 60 days of follow up, was 23%. The median age of the deceased patients was 85 years (IQR=79-93).</p>
</div>
<div type="abstract" xml:lang="en"><p><b>CONCLUSIONS</b>
</p>
<p>We found a high mortality in the first 100 patients diagnosed with COVID-19 at our institution, associated with advanced age and the presence of serious underlying diseases.</p>
</div>
</front>
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<Abstract><AbstractText Label="OBJECTIVE" NlmCategory="OBJECTIVE">There are few descriptions of the clinical presentation and evolution of consecutive SARS-CoV-2 infections with a long-enough follow up.</AbstractText>
<AbstractText Label="METHODS" NlmCategory="METHODS">Description of the first consecutive 100 patients with microbiologically-proven COVID-19 in a large hospital in Madrid, Spain including a minimum of two-month follow up.</AbstractText>
<AbstractText Label="RESULTS" NlmCategory="RESULTS">The median age of the patients (52% males) was 61.5 years (IQR=39.5-82.0) and the median BMI was 28.8 kg/m2 (IQR=24.7-33.7). Overall 72% of the patients had one or more co-morbid conditions with a median age-adjusted Charlson index of 2 (IQR=0-5.7). Five patients (5%) were immunosuppressed. The most common symptoms at the time of diagnosis were fever (80.0%), cough (53.0%) and dyspnea (23.0%). The median O2 saturation at the time of first examination was 94% (IQR=90-97). Chest X-ray on admission was compatible with pneumonia in 63% of the cases (bilateral in 42% and unilateral in 21%). Overall, 30% were managed at home and 70% were admitted to the hospital. Thirteen patients were admitted to the ICU with a median of 11 days of stay in the Unit (IQR=6.0-28.0). CALL score of our population ranged from 4 to 13. Overall, 60.0% of patients received antibiotic treatment and 66.0%, empirical antiviral treatment, mainly with lopinavir/ritonavir (65%) or hydroxychloroquine (42%). Mortality, with a minimum of 60 days of follow up, was 23%. The median age of the deceased patients was 85 years (IQR=79-93).</AbstractText>
<AbstractText Label="CONCLUSIONS" NlmCategory="CONCLUSIONS">We found a high mortality in the first 100 patients diagnosed with COVID-19 at our institution, associated with advanced age and the presence of serious underlying diseases.</AbstractText>
<CopyrightInformation>©The Author 2020. Published by Sociedad Española de Quimioterapia. This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)(https://creativecommons.org/licenses/by-nc/4.0/).</CopyrightInformation>
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The first 100 cases of COVID-19 in a Hospital in Madrid with a 2-month follow-up.

The first 100 cases of COVID-19 in a Hospital in Madrid with a 2-month follow-up.

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